Nuanchan Chutabhakdikul

Assoc. Prof. Nuanchan Chutabhakdikul, Ph.D.

Ph.D. (Neuroscience), Mahidol University, Thailand, 1998
Ext. 1203
Email:   nuanchan.chu@mahidol.ac.th

Research interest

My research interest focuses on the effects of maternal stress on brain development of the offspring e.g., neurogenesis, neural migration, axonal growth, and synapse formation. Recent work focuses on the roles of the placenta barrier in modulating the effects of maternal stress on brain development to understand the underlying mechanism of neurodevelopmental disorders and the possibility of reprogramming. 
 
Another research interest focuses on factors that affect the development of executive function (EF) and self-regulation (SR) in children to adolescents. Our expertise is in measuring EF/SR in young children with the national norms. The ultimate goal is to apply cognitive neuroscience to guide parents and teachers for better child care and education and to improve Thai children’s school learning outcomes.  

Selected Publications

  1. Suppalarkbunlue W, Chutabhakdikul N*, Lertladaluck K, Moriguchi Y. Promoting Inhibitory Control in Preschool Children Through Music-Movement Activities in the Classroom. Journal of Research in Childhood Education. 2022:1-17.

https://doi.org/10.1080/02568543.2022.2111482

  1. Suwaluk A, Chutabhakdikul N*. Altered Development of Prefrontal GABAergic Functions and Anxiety-like Behavior in Adolescent Offspring Induced by Prenatal Stress. Brain Sciences. 2022;12(8). https://doi.org/10.3390/brainsci12081015
  2. Surakul P, Chutabhakdikul N*, Vanichviriyakit R, Promthep K, Thangnipon W. Maternal stress induced autophagy dysfunction and immune activation in the hippocampus of adolescence rat pups. J Chem Neuroanat. 2022;121:102085.

https://doi.org/10.1016/j.jchemneu.2022.102085

  1. Lertladaluck K, Suppalarkbunlue W, Moriguchi Y, Chutabhakdikul N. School-Based Mindfulness Intervention Improves Executive Functions and Self-Regulation in Preschoolers at Risk. TJBS. 2021;16(2):58-72.
  2. Kolaka R, Vanichviriyakit R, Chutabhakdikul N. Effects of maternal stress on Reelin signaling and migration of GABAergic interneurons in the prefrontal cortex of postnatal rats. JMHS. 2021;28(1):40-54.
  3. Chounchay S, Chutabhakdikul N. Effects of deferoxamine on the survival of the neuroblastoma SH-SY5Y cells and neuroimmune response in the BV-2 microglial cells. JMHS. 2020;7(3):100-11.
  4. Lukseng T, Siripornpanich, V, Chutabhakdikul N. Long-Term Vipassana Meditation Enhances Executive Function in Adult Meditators. SMJ. 2020;72(4): 343-51.
  5. Lertladaluck K, Chutabhakdikul N, Chevalier N, Moriguchi Y. Effects of social and nonsocial reward on executive function in preschoolers. Brain Behav. 2020:e01763
  6. Chounchay S, Noctor SC, Chutabhakdikul N. Microglia enhances proliferation of neural progenitor cells in an in vitro model of hypoxic-ischemic injury. EXCLI Journal. 2020;19:950-61.
  7. Siripornpanich V, Visudtibhan A, Kotchabhakdi N, Chutabhakdikul N. Delayed cortical maturation at the centrotemporal brain regions in patients with benign childhood epilepsy with centrotemporal spikes (BCECTS). Epilepsy Res. 2019;154:124-31.
  8. Kolaka R, Chotwiwatthanakun C, Chutabhakdikul N. Fetal exposure to high levels of maternal glucocorticoids alters reelin signaling in the prefrontal cortex of rat pups. Int J Dev Neurosci. 2019;78:185-90.
  9. Seamkhumhom D, Nookong A, Somsiri Rungamornrat S, Chutabhakdikul N. Factors Related to Executive Functions in Preschool-Aged Children. JTNMC. 2019;34(4):80-94.
  10. Siripornpanich V, Sampoon K, Chaithirayanon S, Kotchabhakdi N, and Chutabhakdikul N. Enhancing Brain Maturation Through a Mindfulness-Based Education in Elementary School Children: a Quantitative EEG Study. Mindfulness. 2018;9(6):1877-84.

Full Publications

  1. Suppalarkbunlue W, Chutabhakdikul N*, Lertladaluck K, Moriguchi Y. Promoting Inhibitory Control in Preschool Children Through Music-Movement Activities in the Classroom. J. Res. Child. Educ. 2022:1-17.

https://doi.org/10.1080/02568543.2022.2111482

  1. Suwaluk A, Chutabhakdikul N*. Altered Development of Prefrontal GABAergic Functions and Anxiety-like Behavior in Adolescent Offspring Induced by Prenatal Stress. Brain Sci. 2022;12(8). https://doi.org/10.3390/brainsci12081015
  2. Surakul P, Chutabhakdikul N*, Vanichviriyakit R, Promthep K, Thangnipon W. Maternal stress induced autophagy dysfunction and immune activation in the hippocampus of adolescence rat pups. J Chem Neuroanat. 2022;121:102085.

https://doi.org/10.1016/j.jchemneu.2022.102085

  1. Lertladaluck K, Suppalarkbunlue W, Moriguchi Y, Chutabhakdikul N. School-Based Mindfulness Intervention Improves Executive Functions and Self-Regulation in Preschoolers at Risk. TJBS. 2021;16(2):58-72.
  2. Kolaka R, Vanichviriyakit R, Chutabhakdikul N. Effects of maternal stress on Reelin signaling and migration of GABAergic interneurons in the prefrontal cortex of postnatal rats. JMHS. 2021;28(1):40-54.
  3. Chounchay S, Chutabhakdikul N. Effects of deferoxamine on the survival of the neuroblastoma SH-SY5Y cells and neuroimmune response in the BV-2 microglial cells. JMHS. 2020;7(3):100-11.
  4. Lukseng T, Siripornpanich, V, Chutabhakdikul N. Long-Term Vipassana Meditation Enhances Executive Function in Adult Meditators. SMJ. 2020;72(4): 343-51.
  5. Lertladaluck K, Chutabhakdikul N, Chevalier N, Moriguchi Y. Effects of social and nonsocial reward on executive function in preschoolers. Brain Behav. 2020:e01763
  6. Chounchay S, Noctor SC, Chutabhakdikul N. Microglia enhances proliferation of neural progenitor cells in an in vitro model of hypoxic-ischemic injury. EXCLI Journal. 2020;19:950-61.
  7. Siripornpanich V, Visudtibhan A, Kotchabhakdi N, Chutabhakdikul N. Delayed cortical maturation at the centrotemporal brain regions in patients with benign childhood epilepsy with centrotemporal spikes (BCECTS). Epilepsy Res. 2019;154:124-31.
  8. Kolaka R, Chotwiwatthanakun C, Chutabhakdikul N. Fetal exposure to high levels of maternal glucocorticoids alters reelin signaling in the prefrontal cortex of rat pups. Int J Dev Neurosci. 2019;78:185-90.
  9. Seamkhumhom D, Nookong A, Somsiri Rungamornrat S, Chutabhakdikul N. Factors Related to Executive Functions in Preschool-Aged Children. JTNMC. 2019;34(4):80-94.
  10. Siripornpanich V, Sampoon K, Chaithirayanon S, Kotchabhakdi N, and Chutabhakdikul N. Enhancing Brain Maturation Through a Mindfulness-Based Education in Elementary School Children: a Quantitative EEG Study. Mindfulness. 2018;9(6):1877-84.
  11. Jiraanont P, Sweha SR, AlOlaby RR, Silva M, Tang HT, Durbin-Johnson B, et al. Clinical and molecular correlates in fragile X premutation females. eNeurologicalSci. 2017;7:49-56.
  12. Jiraanont P, Kumar M, Tang HT, Espinal G, Hagerman PJ, Hagerman RJ, et al. Size and methylation mosaicism in males with Fragile X syndrome. Expert Rev Mol Diagn. 2017;17(11):1023-32.
  13. Veerawatananan B, Surakul P, Chutabhakdikul N*. Maternal restraint stress delays maturation of cation-chloride cotransporters and GABAA receptor subunits in the hippocampus of rat pups at puberty. Neurobiol Stress. 2016;3:1-7.
  14. Chutabhakdikul N*, Surakul P. Prenatal stress increased Snk Polo-like kinase 2, SCF beta-TrCP ubiquitin ligase and ubiquitination of SPAR in the hippocampus of the offspring at adulthood. Int J Dev Neurosci. 2013;31(7):560-7.
  15. Surakul P, Weerachatyanukul W, Chutabhakdikul N*. Repeated carbenoxolone injections during late pregnancy alter Snk-SPAR and PSD-95 expression in the hippocampus of rat pups. Neurosci Lett. 2011;494(1):75-9.
  16. Surakul P, Vanichviriyakit R, Weerachatyanukul WA, Jutapakdeegul N*. [P2.03]: Repeated maternal restraint stress down‐regulated NMDA receptor subunits and scaffolding proteins in the hippocampus of postnatal rat. Int J Dev Neurosci. 2010;28(8):686.
  17. Jutapakdeegul N*, Surakul P, Vanichviriyakit R, Weerachatyanukul W. [P2.02]: Repeated carbenoxolone injection during late pregnancy decreased SPAR but increased Snk expression in the hippocampus of rat pups. Int J Dev Neurosci. 2010;28(8):686.
  18. Jutapakdeegul N*, Afadlal S, Polaboon N, Phansuwan-Pujito P, Govitrapong P. Repeated restraint stress and corticosterone injections during late pregnancy alter GAP-43 expression in the hippocampus and prefrontal cortex of rat pups. Int J Dev Neurosci. 2010;28(1):83-90.
  19. Afadlal S, Polaboon N, Surakul P, Govitrapong P, Jutapakdeegul N*. Prenatal stress alters presynaptic marker proteins in the hippocampus of rat pups. Neurosci Lett. 2010;470(1):24-7.
  20. Phansuwan-Pujito P, Saleema L, Mukda S, Tongjaroenbuangam W, Jutapakdeegul N, Casalotti SO, et al. The opioid receptors in inner ear of different stages of postnatal rats. Hear Res. 2003;184(1-2):1-10.
  21. Parnpiansil P, Jutapakdeegul N, Chentanez T, Kotchabhakdi N. Exercise during pregnancy increases hippocampal brain-derived neurotrophic factor mRNA expression and spatial learning in neonatal rat pup. Neurosci Lett. 2003;352(1):45-8.
  22. Jutapakdeegul N, Casalotti SO, Govitrapong P, Kotchabhakdi N. Postnatal touch stimulation acutely alters corticosterone levels and glucocorticoid receptor gene expression in the neonatal rat. Dev Neurosci. 2003;25(1):26-33.

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