Vorasith Siripornpanich

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Assoc. Prof. Vorasith Siripornpanich, M.D., Ph.D.
Dip. Thai Board of Pediatrics
Dip. Thai Board of Pediatric Neurology

Vorasith2Ph.D. (Neurosciences), Mahidol University 2019
Diploma Thai Board of Pediatric Neurology, Mahidol University, 2008 / Diploma Thai Board of Pediatrics, Mahidol University, 2006
Ext:1206
Email: vorasith.sir@mahidol.ac.th, drvorasith@gmail.com
Field of Research :Cognitive Neuroscience

The good quality of people is the most important factor for national development, so I and my research group plan to answer the question “how to improve the cognitive abilities in Thai people” by using both animal and human study models. At animal level, we have been interested in a study of abnormal brain structure and function in experimental epileptic model. We use this model to study both short-term and long-term sequelaes of early-life seizures in animals, which are correspond with neonatal seizure and seizure during childhood period, and observe various changes in central nervous system as well as animal’s behaviors. New information about abnormal cognition and behaviors in this animal model will reveal the knowledge of specific brain region that are responsible for cognitive abilities in living organism and can be applied to understanding of abnormal cognition in many epileptic syndromes in human patients.

          At human level, we have been interested in using electrophysiological tools for study cognitive functions. Electrophysiological tools such as EEG (Electroencephalography), EP (Evoked Potentials), and ERP (Event-Related Potentials) can measure electrical activities of the brain with excellent temporal resolution and able to show information in each brain region under defined condition. We use these equipments for evaluate the brain functions in normal population as well as neurological patient particularly in epileptic patient. Moreover these electrophysiological techniques can be used to compare human cognition before and after neurological intervention such as effects of essential oil inhalation or musical sound learning on attention / concentration domain of cognition. Thus this information from electrophysiological tools provide us a solid data of brain functions and can be integrated with anatomical and molecular data from experimental animal model leading to the knowledge of “functional localization” of cognitive brain areas and also factors that can improve cognitive function in Thai people.

Selected Publications:

Siripornpanich V, Rachiwong S, Ajjimaporn A. A pilot study on salivary cortisol secretion and auditory P300 event-related potential in patients with physical disability-related stress. Int J Neurosci. 2020;130(2):170-175.

Siripornpanich V, Visudtibhan A, Kotchabhakdi N, Chutabhakdikul N. Delayed cortical maturation at the centrotemporal brain regions in patients with benign childhood epilepsy with centrotemporal spikes (BCECTS). Epilepsy Res. 2019;154:124-131.

Ajjimaporn A, Ramyarangsi P, Siripornpanich V. Effects of a 20-min Nap after Sleep Deprivation on Brain Activity and Soccer Performance [published online ahead of print, 2020 Jul 6]. Int J Sports Med. 2020;10.1055/a-1192-6187. doi:10.1055/a-1192-6187

Sayorwan W, Siripornpanich V, Piriyapunyaporn T, Hongratanaworakit T, Kotchabhakdi N, Ruangrungsi N. The effects of lavender oil inhalation on emotional states, autonomic nervous system, and brain electrical activity. J Med Assoc Thai. 2012;95(4):598-606.

Sayorwan W, Ruangrungsi N, Piriyapunyporn T, Hongratanaworakit T, Kotchabhakdi N, Siripornpanich V. Effects of inhaled rosemary oil on subjective feelings and activities of the nervous system. Sci Pharm. 2013;81(2):531-542. doi:10.3797/scipharm.1209-05.

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