ผู้ช่วยศาสตราจารย์ ดร. นสพ.นริศร กิติยานันท์

Our major goal is to promote the development of innovative discoveries and translational strategies related to stem cells. We are interested in understanding the mechanisms of blood and neural development, modeling blood and neural disorders, and direct converting of adult fibroblast into other specific lineage.

Currently, we are developing integration-free induced pluripotent stem (iPS) cells from both animal and human sources, either healthy or patients with known genetic diseases. The cells will be expanded in culture, used for basic science studies, genetically modified with state-of-the-art genome editing technology, differentiate into specific lineages, and further used for either transplantation in animal models of diseases or for drug/chemical compound screening.

We also aim to create a highly innovative international collaboration. One of our ongoing projects (STEMMAD) has been supported by the European Union under the scope of FP7-PEOPLE-2012-IAPP, to work together with 2 R&D SMEs and other 2 prestigious academic institutes in Europe.

Selected Publications

1.Thangnipon W, Puangmalai N, Chinchalongporn V, Jantrachotechatchawan C, Kitiyanant N, Soiampornkul, Tuchinda P, Nobsathian S. N-benzylcinnamide protects rat cultured cortical neurons from β-amyloid peptide-induced neurotoxicity. Neurosci Lett 2013, 556:20-5. doi:10.1016/j.neulet.2013.09.071.

2.Thangnipon W, Suwanna N, Kitiyanant N, Soiampornkul R, Tuchinda P, Munyoo B, Nobsathian S. Protective role of N-trans-feruloyltymine against β-amyloid peptide-induced neurotoxicity in rat cultured cortical neurons. Neurosci Lett 2012, 513(4): 229-232. doi: 10.1016/j.neulet2012.02.047.

3.Kitiyanant N, Kitiyanant Y, Svendsen CN and Thangnipon W. BDNF-, IGF-1 and GDNF-secreting human neural progenitor cells rescue amyloid β-induced toxicity in cultured rat septal neurons. Neurochem Res 2012, 37(1): 143-52. doi:10.1007/s11064-011-0592-1.

4.Saikhun J, Kitiyanant N, Songtaveesin C, Pavasuthipaisit K and Kitiyanant Y. Development of swamp buffalo (Bubalus bubalis) embryos after parthenogenetic activation and nuclear transfer using serum fed or starved fetal fibroblasts. Reprod Nutr Dev 2004, 44(1): 65-78.

Book Chapter:

Suzuki M, McHugh J and Kitiyanant N. (2011) Human neural stem/progenitor cells: Mitotic and neurogenic effects of growth factors, neurosteroids, and excitatory amino acids. In: Hormones in Neurodegeneration, Neuroprotection and Neurogenesis. (Gravanis, A. and Mellon, S. Eds), Wiley-Blackwell, pp. 331-345.

Full Publications

1.*Thangnipon W, Puangmalai N, Chinchalongporn V, Jantrachotechatchawan C, Kitiyanant N, Sai-ampornkul, Tuchinda P, Nobsathian S. N-benzylcinnamide protects rat cultured cortical neurons from β-amyloid peptide-induced neurotoxicity. Neurosci Lett 2013, 556:20-5. doi:10.1016/j.neulet.2013.09.071.

2.*Thangnipon W, Suwanna N, Kitiyanant N, Soiampornkul R, Tuchinda P, Munyoo B, Nobsathian S. Protective role of N-trans-feruloyltymine against β-amyloid peptide-induced neurotoxicity in rat cultured cortical neurons. Neurosci Lett 2012, 513(4): 229-232. doi: 10.1016/j.neulet2012.02.047.

3.Kitiyanant N, Kitiyanant Y, Svendsen CN and *Thangnipon W. BDNF-, IGF-1 and GDNF-secreting human neural progenitor cells rescue amyloid β-induced toxicity in cultured rat septal neurons. Neurochem Res 2012, 37(1): 143-52. doi:10.1007/s11064-011-0592-1.

4.Saikhun J, Kitiyanant N, Songtaveesin C, Pavasuthipaisit K and *Kitiyanant Y. Development of swamp buffalo (Bubalus bubalis) embryos after parthenogenetic activation and nuclear transfer using serum fed or starved fetal fibroblasts. Reprod Nutr Dev 2004, 44(1): 65-78.