{"id":744,"date":"2025-06-19T22:10:21","date_gmt":"2025-06-19T15:10:21","guid":{"rendered":"https:\/\/mb-dev.mahidol.ac.th\/mumb\/?page_id=744"},"modified":"2026-03-05T10:08:04","modified_gmt":"2026-03-05T03:08:04","slug":"saovaros-profile","status":"publish","type":"page","link":"https:\/\/mb.mahidol.ac.th\/th\/saovaros-profile\/","title":{"rendered":"saovaros-profile"},"content":{"rendered":"\n

\u0e14\u0e23. \u0e21.\u0e25.\u0e40\u0e2a\u0e32\u0e27\u0e23\u0e2a \u0e2a\u0e27\u0e31\u0e2a\u0e14\u0e34\u0e27\u0e31\u0e12\u0e19\u0e4c
\u0e23\u0e2d\u0e07\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c<\/span>\u00a0\u2003<\/span><\/p><\/div><\/div><\/div>\n\n\n\n

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\"M.L.<\/a><\/div>

M.L. Saovaros Svasti, Ph.D.<\/h1>

Associate Professor<\/h4>

<\/a> <\/a> <\/a><\/center><\/div>
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<\/i> ………………………………………….<\/span><\/i><\/span><\/p><\/blockquote>\n\n\n\n

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\u00a0Tel: 66 (0) 2441-9003 \u2013 7 Ext. 1357
\u00a0Email: saovaros.svamahidol.ac.th
\u00a0Ph.D. (Biochemistry), Mahidol University,Thailand, 1998
Academic Program(s)
Molecular Genetics and Genetic Engineering<\/a>
Molecular and Integrative Biosciences<\/a><\/p><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n\n\n\n

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Research Summary<\/span>\u00a0\u2003<\/span><\/p><\/div><\/div><\/div>\n\n\n\n

Saovaros research interests are regulation of erythropoiesis and mechanism of ineffective erythropoiesis, novel therapy for thalassemia by antisense oligonucleotide and HbF inducer. She is also working on clinical complications of thalassemia including hypercoagulable states, infection and diabetes.<\/p><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n\n\n\n

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Selected Publications<\/span>\u00a0\u2003<\/span><\/p><\/div><\/div><\/div>\n\n\n\n

1.d\u2019Arqom A, Nualkaew T, Jearawiriyapaisarn N, Kole R, Svasti S. Engineered U7 snRNA restores correct \u03b2-globin pre-mRNA splicing in mouse \u03b2IVS2-654-thalassemic erythroid progenitor cells. Hum Gene Ther. 2021;32(9-10):473-480.
2.Munkongdee T, Tongsima S, Ngamphiw C, Wangkumhang P, Peerapittayamongkol C, Hashim HB, Fucharoen S, Svasti S. Predictive SNPs for \u03b20-thalassemia\/HbE disease severity. Sci Rep. 2021;11(1):10352.
3.Nuamsee K, Chuprajob T, Pabuprapap W, Jintaridth P, Munkongdee T, Phannasil P, Vadolas J, Chaichompoo P, Suksamrarn A, Svasti S. Trienone analogs of curcuminoids induce fetal hemoglobin synthesis via demethylation at G\u03b3-globin gene promoter. Sci Rep. 2021;11(1):8552.
4.Nualkaew T, Jearawiriyapaisarn N, Hongeng S, Fucharoen S, Kole R, Svasti S. Restoration of correct \u03b2IVS2-654-globin mRNA splicing and HbA production by engineered U7 snRNA in \u03b2-thalassaemia\/HbE erythroid cells. Sci Rep. 2019;9(1):7672.
5.Kheansaard W, Phongpao K, Paiboonsukwong K, Pattanapanyasat K, Chaichompoo P, Svasti S. Microparticles from \u03b2-thalassaemia\/HbE patients induce endothelial cell dysfunction. Sci Rep. 2018;8(1):13033.<\/p><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n\n\n\n

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\r\n\r\n\"pubmed\"<\/a>\r\n\r\n<\/div>\n<\/div><\/div><\/div><\/div><\/div>\n
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