{"id":758,"date":"2025-06-19T22:13:27","date_gmt":"2025-06-19T15:13:27","guid":{"rendered":"https:\/\/mb-dev.mahidol.ac.th\/mumb\/?page_id=758"},"modified":"2026-03-05T11:10:39","modified_gmt":"2026-03-05T04:10:39","slug":"sujira-profile","status":"publish","type":"page","link":"https:\/\/mb.mahidol.ac.th\/th\/sujira-profile\/","title":{"rendered":"sujira-profile"},"content":{"rendered":"\n<div class=\"wp-block-essential-blocks-advanced-heading  root-eb-advance-heading-9pcp5\"><div class=\"eb-parent-wrapper eb-parent-eb-advance-heading-9pcp5 \"><div class=\"eb-advance-heading-wrapper eb-advance-heading-9pcp5 button-1 undefined\" data-id=\"eb-advance-heading-9pcp5\"><p class=\"eb-ah-title\"><span class=\"first-title\">\u0e14\u0e23.\u0e2a\u0e38\u0e08\u0e34\u0e23\u0e32 \u0e21\u0e38\u0e01\u0e14\u0e32 <br>\u0e23\u0e2d\u0e07\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c<\/span>\u00a0<span class=\"second-title\">\u2003<\/span><\/p><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-essential-blocks-wrapper alignwide  root-eb-wrapper-z238t\"><div class=\"eb-parent-wrapper eb-parent-eb-wrapper-z238t \"><div class=\"eb-wrapper-outer eb-wrapper-z238t eb-wrapper-align-center\"><div class=\"eb-wrapper-inner\"><div class=\"eb-wrapper-inner-blocks\">\n<div class=\"wp-block-essential-blocks-row alignfull  root-eb-row-g3ocze3\"><div class=\"eb-parent-wrapper eb-parent-eb-row-g3ocze3 \"><div class=\"eb-row-root-container eb-row-g3ocze3\" data-id=\"eb-row-g3ocze3\"><div class=\"eb-row-wrapper\"><div class=\"eb-row-inner\">\n<div class=\"wp-block-essential-blocks-column  root-eb-column-tycs9ej\"><div class=\"eb-parent-wrapper eb-parent-eb-column-tycs9ej \"><div class=\"eb-column-wrapper eb-column-tycs9ej\"><div class=\"eb-column-inner\">\n<div class=\"wp-block-essential-blocks-team-member  root-eb-team-member-f6tjw\"><div class=\"eb-parent-wrapper eb-parent-eb-team-member-f6tjw \"><div class=\"eb-team-member-f6tjw eb-team-wrapper preset3  \"><div class=\"eb-team-inner\"><div class=\"eb-team-member-image\"><a href=\"\/th\/sujira-profile\/\" rel=\"noopener\"><img decoding=\"async\" class=\"eb-team-member-avatar\" src=\"https:\/\/mb.mahidol.ac.th\/th\/wp-content\/uploads\/2026\/01\/sujira.muk_.jpg\" alt=\"Sujira Mukda, Ph.D.\"\/><\/a><\/div><div class=\"eb-team-member-contents\"><div class=\"eb-team-member-texts\"><h1 class=\"eb-team-member-name\">Sujira Mukda, Ph.D.<\/h1><h4 class=\"eb-team-member-job-title\">Associate Professor<\/h4><p class=\"eb-team-member-description\"><div style=\"align: center; float: center; margin-top: 10px;\"><center><a title=\"animal biology\" href=\"https:\/\/mb.mahidol.ac.th\/th\/animal-biology\/\"><img decoding=\"async\" src=\"https:\/\/mb.mahidol.ac.th\/wp-content\/uploads\/2025\/11\/Animal-Biology-2.png\" style=\"max-width: 32px;\" \/><\/a> <a href=\"https:\/\/mb.mahidol.ac.th\/th\/molecular-biology\/\" title=\"Molecular Biology\"><img decoding=\"async\" src=\"https:\/\/mb.mahidol.ac.th\/wp-content\/uploads\/2025\/11\/Molecular-Biology-2.png\" style=\"max-width: 32px;\" \/><\/a> <a href=\"https:\/\/mb.mahidol.ac.th\/th\/cognitive-biology\/\" title=\"Cognitive science\"><img decoding=\"async\" src=\"https:\/\/mb.mahidol.ac.th\/wp-content\/uploads\/2025\/11\/Cognitive-Science-2.png\" style=\"max-width: 32px;\" \/><\/a><\/center><\/div><\/p><\/div><\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-essential-blocks-column  root-eb-column-fu6m7zn\"><div class=\"eb-parent-wrapper eb-parent-eb-column-fu6m7zn \"><div class=\"eb-column-wrapper eb-column-fu6m7zn\"><div class=\"eb-column-inner\">\n<div class=\"wp-block-essential-blocks-wrapper alignfull  root-eb-wrapper-xlprb\"><div class=\"eb-parent-wrapper eb-parent-eb-wrapper-xlprb \"><div class=\"eb-wrapper-outer eb-wrapper-xlprb\"><div class=\"eb-wrapper-inner\"><div class=\"eb-wrapper-inner-blocks eb-wrapper-align-center\">\n<blockquote><p style=\"text-align: center;\"><span><i class=\"fa fa-quote-left \" style=\"color: #e2a660; font-size: 30px; \"><\/i> <span style=\"font-size: 22px; \">Since the neuronal cell death causes\nmany pathological consequences,\npreventing its occurrence and understanding\nits underlying mechanism become a crucial issue.<\/span><i class=\"fa fa-quote-right \" style=\"color: #e2a660; font-size: 30px;\"><\/i><\/span><\/p><\/blockquote>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-essential-blocks-text  root-eb-text-iyj7s\"><div class=\"eb-parent-wrapper eb-parent-eb-text-iyj7s \"><div class=\"eb-text-wrapper eb-text-iyj7s\" data-id=\"eb-text-iyj7s\"><p class=\"eb-text\">Tel: 66 (0) 2441-9003 \u2013 7 Ext. 1206<br>Email: sujira.muk<img decoding=\"async\" src=\"https:\/\/mb.mahidol.ac.th\/web\/wp-content\/uploads\/2023\/09\/atsign.png\">mahidol.ac.th<br>Ph.D. (Neurosciences), Mahidol University, 2006<br>Academic Program(s)<br><a href=\"https:\/\/mb.mahidol.ac.th\/th\/academic-neuroscience\/\">Neuroscience<\/a><br><a href=\"https:\/\/mb.mahidol.ac.th\/th\/academic-mbmb\/\">Molecular and Integrative Biosciences<\/a><\/p><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-essential-blocks-wrapper alignfull  root-eb-wrapper-my7aj85\"><div class=\"eb-parent-wrapper eb-parent-eb-wrapper-my7aj85 \"><div class=\"eb-wrapper-outer eb-wrapper-my7aj85 eb-wrapper-align-center\"><div class=\"eb-wrapper-inner\"><div class=\"eb-wrapper-inner-blocks\">\n<div class=\"wp-block-essential-blocks-row alignfull  root-eb-row-4c96e\"><div class=\"eb-parent-wrapper eb-parent-eb-row-4c96e \"><div class=\"eb-row-root-container eb-row-4c96e\" data-id=\"eb-row-4c96e\"><div class=\"eb-row-wrapper\"><div class=\"eb-row-inner\">\n<div class=\"wp-block-essential-blocks-column  root-eb-column-vhy7e\"><div class=\"eb-parent-wrapper eb-parent-eb-column-vhy7e \"><div class=\"eb-column-wrapper eb-column-vhy7e\"><div class=\"eb-column-inner\">\n<div class=\"wp-block-essential-blocks-wrapper alignwide  root-eb-wrapper-dsqr1\"><div class=\"eb-parent-wrapper eb-parent-eb-wrapper-dsqr1 \"><div class=\"eb-wrapper-outer eb-wrapper-dsqr1 eb-wrapper-align-center\"><div class=\"eb-wrapper-inner\"><div class=\"eb-wrapper-inner-blocks\">\n<div class=\"wp-block-essential-blocks-advanced-heading  root-eb-advance-heading-cb8ai\"><div class=\"eb-parent-wrapper eb-parent-eb-advance-heading-cb8ai \"><div class=\"eb-advance-heading-wrapper eb-advance-heading-cb8ai button-1 undefined\" data-id=\"eb-advance-heading-cb8ai\"><p class=\"eb-ah-title\"><span class=\"first-title\">Research Summary<\/span>\u00a0<span class=\"second-title\">\u2003<\/span><\/p><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-essential-blocks-text  root-eb-text-unlmw\"><div class=\"eb-parent-wrapper eb-parent-eb-text-unlmw \"><div class=\"eb-text-wrapper eb-text-unlmw\" data-id=\"eb-text-unlmw\"><p class=\"eb-text\">Our current research interests are primarily on the neurobiological consequences of drug abuse and addiction on the brain and behaviors. The purpose of our work aims to approach the vulnerabilities of addiction emphasizing on the neurotoxicity, neuronal cell degeneration, neuroinflammation, cognitive impairment, and neurodevelopmental deficits, as well as the accompanying changes in the brain areas involved in drug addiction and cognition.<br><br>In addition, our research interests are also focusing on how drugs of abuse impact the molecular and physiological circadian clocks, and vice versa, how disruption of the circadian rhythms plays a key part in regulating the brain\u2019s reward-related pathways. The therapeutic approach that reset the circadian rhythm contributes to clock-drug interactions will also be studied.<br><br>Another research study in our lab is focusing on the neurobiological consequences of cerebrovascular disease (stroke), particularly after a transient ischemic stroke, which results in neuronal cell death and eventually leads to serious neurological consequences including cognitive impairments and dementia. Our research aims are focusing on the signaling molecules crucial for memory formation, and develop the therapeutic approaches to slow down the progression of memory and cognitive deficits after stroke.<\/p><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-essential-blocks-row alignfull  root-eb-row-jrlte\"><div class=\"eb-parent-wrapper eb-parent-eb-row-jrlte \"><div class=\"eb-row-root-container eb-row-jrlte\" data-id=\"eb-row-jrlte\"><div class=\"eb-row-wrapper\"><div class=\"eb-row-inner\">\n<div class=\"wp-block-essential-blocks-column  root-eb-column-hlczi\"><div class=\"eb-parent-wrapper eb-parent-eb-column-hlczi \"><div class=\"eb-column-wrapper eb-column-hlczi\"><div class=\"eb-column-inner\">\n<div class=\"wp-block-essential-blocks-wrapper alignwide  root-eb-wrapper-tyv8a\"><div class=\"eb-parent-wrapper eb-parent-eb-wrapper-tyv8a \"><div class=\"eb-wrapper-outer eb-wrapper-tyv8a\"><div class=\"eb-wrapper-inner\"><div class=\"eb-wrapper-inner-blocks eb-wrapper-align-center\">\n<div class=\"wp-block-essential-blocks-advanced-heading  root-eb-advance-heading-iz4r0\"><div class=\"eb-parent-wrapper eb-parent-eb-advance-heading-iz4r0 \"><div class=\"eb-advance-heading-wrapper eb-advance-heading-iz4r0 button-1 undefined\" data-id=\"eb-advance-heading-iz4r0\"><p class=\"eb-ah-title\"><span class=\"first-title\">Selected Publications<\/span>\u00a0<span class=\"second-title\">\u2003<\/span><\/p><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-essential-blocks-text  root-eb-text-7emo9\"><div class=\"eb-parent-wrapper eb-parent-eb-text-7emo9 \"><div class=\"eb-text-wrapper eb-text-7emo9\" data-id=\"eb-text-7emo9\"><p class=\"eb-text\">1.Pe LS, Pe KCS, Panmanee J, Govitrapong P, Yang JL,\u00a0<strong>Mukda S<\/strong>. Plausible therapeutic effects of melatonin and analogs in the dopamine-associated pathophysiology of bipolar disorder. J Psychiatr Res. 2025;182:13-20.<br><br>2.Panmanee J, Charoensutthivarakul S, Cheng CW, Promthep K,\u00a0<strong>Mukda S<\/strong>, Prasertporn T, et al. A Complex Interplay Between Melatonin and RORbeta: RORbeta is Unlikely a Putative Receptor for Melatonin as Revealed by Biophysical Assays. Mol Neurobiol. 2025;62(2):2333-47.<br><br>3.Viwatpinyo K,\u00a0<strong>Mukda S<\/strong>, Warinhomhoun S. Effects of mitragynine on viability, proliferation, and migration of C6 rat glioma, SH-SY5Y human neuroblastoma, and HT22 immortalized mouse hippocampal neuron cell lines. Biomed Pharmacother. 2023;166:115364.<br><br>4.Promthep K, Nopparat C,\u00a0<strong>Mukda S<\/strong>, Pannengpetch S, Wisomka P, Chantadul V, et al. Proteomic profiling reveals neuronal ion channel dysregulation and cellular responses to DNA damage-induced cell cycle arrest and senescence in human neuroblastoma SH-SY5Y cells exposed to cypermethrin. Neurotoxicology. 2022;93:71-83.<br><br>5.Hsu SY, Chen CH,\u00a0<strong>Mukda S<\/strong>, Leu S. Neuronal Pnn Deficiency Increases Oxidative Stress and Exacerbates Cerebral Ischemia\/Reperfusion Injury in Mice. Antioxidants (Basel). 2022;11(3).<br><br>6.Veschsanit N, Yang JL, Ngampramuan S, Viwatpinyo K, Pinyomahakul J, Lwin T, Chancharoen, P, Rungruang, S, Govitrapong, P,\u00a0<strong>Mukda, S<\/strong>. Melatonin reverts methamphetamine-induced learning and memory impairments and hippocampal alterations in mice. Life Sci. 2021;265:118844.<br><br>7.Lwin T, Yang JL, Ngampramuan S, Viwatpinyo K, Chancharoen P, Veschsanit N, Pinyomahakul J, Govitrapong P,\u00a0<strong>Mukda, S<\/strong>. Melatonin ameliorates methamphetamine-induced cognitive impairments by inhibiting neuroinflammation via suppression of the TLR4\/MyD88\/NFkappaB signaling pathway in the mouse hippocampus. Prog Neuropsychopharmacol Biol Psychiatry. 2021;111:110109.<br><br>8.Yang JL, Chen WY,\u00a0<strong>Mukda S<\/strong>, Yang YR, Sun SF, Chen SD. Oxidative DNA damage is concurrently repaired by base excision repair (BER) and apyrimidinic endonuclease 1 (APE1)-initiated nonhomologous end joining (NHEJ) in cortical neurons. Neuropathol Appl Neurobiol. 2020;46(4):375-90.<br><br>9.Hsu SY,\u00a0<strong>Mukda S<\/strong>, Leu S. Expression and Distribution Pattern of Pnn in Ischemic Cerebral Cortex and Cultured Neural Cells Exposed to Oxygen-Glucose Deprivation. Brain Sci. 2020;10(10).<br><br>10.<strong>Mukda S<\/strong>, Tsai CY, Leu S, Yang JL, Chan SHH. Pinin protects astrocytes from cell death after acute ischemic stroke via maintenance of mitochondrial anti-apoptotic and bioenergetics functions. J Biomed Sci. 2019;26(1):43.<br><br>11.Yang JL,\u00a0<strong>Mukda S<\/strong>, Chen SD. Diverse roles of mitochondria in ischemic stroke. Redox Biol. 2018;16:263-75.<\/p><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-essential-blocks-advanced-heading  root-eb-advance-heading-svnbk\"><div class=\"eb-parent-wrapper eb-parent-eb-advance-heading-svnbk \"><div class=\"eb-advance-heading-wrapper eb-advance-heading-svnbk button-1 undefined\" data-id=\"eb-advance-heading-svnbk\"><p class=\"eb-ah-title\"><span class=\"first-title\">Awards &#038; Scholarships:<\/span>\u00a0<span class=\"second-title\">\u2003<\/span><\/p><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-essential-blocks-text  root-eb-text-4lk1t\"><div class=\"eb-parent-wrapper eb-parent-eb-text-4lk1t \"><div class=\"eb-text-wrapper eb-text-4lk1t\" data-id=\"eb-text-4lk1t\"><p class=\"eb-text\">1.IBRO World Congress Travel Grants 2023<br>2.\u0e23\u0e32\u0e07\u0e27\u0e31\u0e25\u0e1a\u0e38\u0e04\u0e25\u0e32\u0e01\u0e23\u0e14\u0e35\u0e40\u0e14\u0e48\u0e19\u0e02\u0e2d\u0e07\u0e2a\u0e16\u0e32\u0e1a\u0e31\u0e19\u0e0a\u0e35\u0e27\u0e27\u0e34\u0e17\u0e22\u0e32\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e42\u0e21\u0e40\u0e25\u0e01\u0e38\u0e25 \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25 \u0e1b\u0e23\u0e30\u0e08\u0e33\u0e1b\u0e35 2565 (2022 Outstanding Personnel Award of the Institute of Molecular Biosciences, Mahidol University)<br>3.\u0e23\u0e32\u0e07\u0e27\u0e31\u0e25\u0e2b\u0e49\u0e2d\u0e07\u0e1b\u0e0f\u0e34\u0e1a\u0e31\u0e15\u0e34\u0e01\u0e32\u0e23\u0e15\u0e49\u0e19\u0e41\u0e1a\u0e1a\u0e14\u0e49\u0e32\u0e19\u0e04\u0e27\u0e32\u0e21\u0e1b\u0e25\u0e2d\u0e14\u0e20\u0e31\u0e22\u0e43\u0e19\u0e2b\u0e49\u0e2d\u0e07\u0e1b\u0e0f\u0e34\u0e1a\u0e31\u0e15\u0e34\u0e01\u0e32\u0e23\u0e17\u0e35\u0e48\u0e40\u0e01\u0e35\u0e48\u0e22\u0e27\u0e02\u0e49\u0e2d\u0e07\u0e01\u0e31\u0e1a\u0e2a\u0e32\u0e23\u0e40\u0e04\u0e21\u0e35\u0e1b\u0e23\u0e30\u0e08\u0e33\u0e1b\u0e35 2563 (2020 Outstanding Research Laboratory on Fire and Chemical Safety, following ESPReL standard)<br>4.International Brain Research Organization (IBRO) Research Fellowship 2016<br>5.International Society for Neurochemistry (ISN) \u2013 Committee for Aid and Education in Neurochemistry (CAEN) Research Award Category 1A 2015<\/p><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-essential-blocks-wrapper alignfull  root-eb-wrapper-utkjw\"><div class=\"eb-parent-wrapper eb-parent-eb-wrapper-utkjw \"><div class=\"eb-wrapper-outer eb-wrapper-utkjw eb-wrapper-align-center\"><div class=\"eb-wrapper-inner\"><div class=\"eb-wrapper-inner-blocks\">\n<div style=\"float: center; margin-top: 30px;\">\r\n\r\n<a rel=\"noopener noreferrer\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Sujira++Mukda%5BAuthor+-+Full%5D\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/mb.mahidol.ac.th\/images\/pubmed\/pubmed.png\" alt=\"pubmed\" \/><\/a>\r\n\r\n<\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<div class=\"pvc_clear\"><\/div><p id=\"pvc_stats_758\" class=\"pvc_stats total_only  \" data-element-id=\"758\" style=\"\"><i class=\"pvc-stats-icon medium\" 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