The main area of my research interests is focusing on neurodegeneration, neuroprotection and neurorestoration especially the death and survival signaling in neuronal cell and the protective roles of melatonin on the neurodegeneration. Moreover, the neurotoxic effects of drug abuse such as methamphetamine on neurodegeneration, neuroinflammation and cognitive impairment are also the aim of our study.

1.Kraiwattanapirom N, Komlao P, Harnpramukkul A, Promyo K, Ngampramuan S, Chetsawang B. The neuroprotective role of melatonin against methamphetamine toxicity-induced neurotransmission dysregulation and cognitive deficits in rats. Food Chem Toxicol. 2021 Nov;157:112610. doi: 10.1016/j.fct.2021.112610.

2.Promyo K, Iqbal F, Chaidee N, Chetsawang B. Aluminum chloride-induced amyloid β accumulation and endoplasmic reticulum stress in rat brain are averted by melatonin. Food Chem Toxicol. 2020 Oct 29:111829. doi: 10.1016/j.fct.2020.111829.

3.Hein ZM, Kraiwattanapirom N, Mukda S, Chetsawang B. The induction of Neuron-Glial2 (NG2) expressing cells in methamphetamine toxicity-induced neuroinflammation in rat brain are averted by melatonin. J Neuroimmunol 2020; Jul 15;344:577232. doi: 10.1016/j.jneuroim.2020.577232. Epub 2020 Apr 4.

4.Premratanachai A, Suwanjang W, Govitrapong P, Chetsawang J, Chetsawang B. Melatonin prevents calcineurin-activated the nuclear translocation of nuclear factor of activated T-cells in human neuroblastoma SH-SY5Y cells undergoing hydrogen peroxide-induced cell death. J Chem Neuroanat. 2020 Jul;106:101793. doi: 10.1016/j.jchemneu.2020.101793. Epub 2020 Apr 26.

5.Chetsawang B, Putthaprasart C, Phansuwan-Pujito P, Govitrapong P. Melatonin protects against hydrogen peroxide-induced cell death signaling in SH-SY5Y cultured cells: involvement of nuclear factor kappa B, Bax and Bcl-2. J. Pineal Res. 2006; 41:116-123.