Neuroscience International Program
M.Sc. & Ph.D.
Academic Programs
1.Electrophysiology and Neuroimaging Techniques
- EEG studies on cognitive interventions
Measuring brain activity before and after cognitive interventions to assess brain plasticity and functional improvements. - Event-related potential (ERP) analyses in neurological diseases
Using ERP techniques to detect early signs of nervous system disorders and monitor brain function changes. - Role of sleep and circadian rhythm in cognition
Exploring how sleep patterns and biological clocks influence memory formation, attention, and learning abilities.
2.Child and Adolescent Brain Development
- Sleep deprivation and executive function in children and adolescents
Investigating how insufficient sleep impacts attention, memory, language processing, and decision-making skills in school-aged children and teenagers. - Development of metacognitive skills and academic success
Investigating how children’s ability to think about their own thinking relates to their school performance over time. - Enhancing prosocial behavior through brain imaging and games
Using collaborative tasks and neuroeconomic games to understand and promote prosocial decision-making in young people.
3.Neurodegeneration and Neuroprotection
- Regulation of tryptophan metabolism in neuroinflammation
Exploring how controlling tryptophan pathways can prevent cognitive impairments caused by methamphetamine-induced brain inflammation in animal models. - Mechanisms of pyroptotic cell death in cognitive impairment
Studying how inflammation-driven cell death contributes to memory and cognitive decline after methamphetamine exposure. - Discovery of orexin receptor antagonists for insomnia treatment
Investigating new compounds that block orexin receptors as a novel therapeutic strategy for sleep disorders. - Natural compound-based drug discovery for Alzheimer’s disease
Identifying and testing small molecules derived from natural sources that could slow down or prevent Alzheimer’s disease progression.
4.Biomarkers and Pathogenesis of Brain Disorders
- Biomarkers for brain and psychiatric disorders
Searching for biological indicators that could lead to earlier diagnosis and better understanding of brain developmental and psychiatric conditions. - Astrocytic signaling in stroke injury
Investigating how brain support cells (astrocytes) respond during ischemic events and contribute to brain damage and repair. - Cerebrovascular pathology in thalassemia
Studying how vascular changes in genetic blood disorders like thalassemia can affect cognitive function using mouse models.
5.Stem Cell Research and Extracellular Vesicles
- Engineered extracellular vesicles for heart regeneration
Developing bioengineered vesicles from stem cells to promote heart cell survival and regeneration after injury. - Anti-aging effects of stem cell-derived exosomes
Studying how exosomes from young stem cells can rejuvenate aging neurons and restore brain function. - Preconditioned microglia exosomes for neuroprotection
Investigating how microglia, treated with anti-aging compounds, secrete protective vesicles that may enhance brain resilience.
6.Drug Discovery and Structure-Based Design
- IDO-1 inhibitors for neuroinflammatory diseases
Designing small molecules that inhibit the IDO-1 enzyme, a key player in brain inflammation and degeneration. - Computer-aided drug discovery for Alzheimer’s therapeutics
Using advanced modeling and simulation tools to find new drug candidates that target mechanisms underlying Alzheimer’s disease. - Neurotoxicity of organophosphate pesticides
Studying how common agricultural chemicals can cause long-term damage to the nervous system and increase the risk of brain diseases.
7.Biosensors and Nanotechnology for Neuroscience
- Colorimetric biosensors for stress monitoring
Developing simple color-change biosensors that detect stress-related biomarkers in biological samples. - Immunosensors for early Alzheimer’s disease detection
Creating sensitive sensors that can identify Alzheimer’s disease biomarkers at early stages for potential diagnosis tools. - Nanomaterials for biological and medical applications
Exploring the use of engineered nanoparticles to improve biosensor sensitivity and therapeutic delivery systems.
8. OMICs Technologies in Neuroscience
- Transcriptomic and proteomic profiling of neuron development
Analyzing gene and protein expression changes during the growth and differentiation of neuronal cells.
- Stem cell secretome for rejuvenating aging cells
Developing secreted factor cocktails from stem cells to promote repair and rejuvenation of aging tissues.
