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Kittiphong Paiboonsukwong, M.D., Ph.D.

Epidemiological and clinical research on thalassemia to better understanding of thalassemia disease and improve quality of life of the patients.

  • Tel: 66 (0) 2441-9003 – 7 Ext. 1312
  • Email: kittiphong.paimahidol.ac.th
  • Ph.D. (Molecular Genetics and Genetic Engineering), Mahidol University, 2004
  • Academic Program(s)

      Thalassemia and abnormal hemoglobin are the most common monogenic disorders and it has been estimated that approximately 5.2% of the world population are carriers. It has been estimated that the conception of homozygous beta-thalassemia and beta-thalassemia/Hb E in Southeast Asia is 0.24 and 0.25 per 1000 birth, respectively. Many thousands of these beta-thalassemia disorders are living in Southeast Asia. The alpha-thalassemia is widespread throughout Southeast Asia in which 5-15% of the population had some form of alpha-thalassemias. Because of high prevalence of both alpha thalassemia-1 and alpha- thalassemia-2 in these populations, HbH disease and Hb Bart’s hydrops fetalis are seen frequently. This causes public health burden for the region. Increasing number of labor migration among Southeast Asian countries pose a major problem in prevention, control and prenatal diagnosis for thalassemia disease in this area due to a difficult characterization of uncommon or unique mutations. Up-to-date epidemiological data and nature of thalassemia mutations are still lacking in many countries in this region. Reliable data is needed to provide evidence of the public health burden in order to develop the national control programs.

      A multicenter was designed to collect epidemiological, clinical and therapeutic information on thalassemia patients in Southeast Asian countries. Thalassemia diagnosis will be performed by complete blood cell (CBC) measurement, hemoglobin typing and DNA analysis.

1.Paiboonsukwong K, Ohbayashi F, Shiiba H, Aizawa E, Yamashita T, Mitani K. Correction of mutant Fanconi anemia gene by homologous recombination in human hematopoietic cells using adeno-associated virus vector. J Gene Med. 2009 Nov;11(11):1012-9.

2.Buakhao J, Khumpun P, Winichagoon P, Fucharoen S, Paiboonsukwong K. Prevalence and characterization of thalassemia among migrant workers from Cambodia, Lao PDR and Myanmar in Thailand. Southeast Asian J Trop Med Public Health. 2017 Jul;48:4:864-874.

3.Munkongdee T, Chen P, Winichagoon P, Fucharoen S and Paiboonsukwong K. Update in Laboratory Diagnosis of Thalassemia. Front. Mol. Biosci., 27 May 2020. https://doi.org/10.3389/fmolb.2020.00074

4.Munkongdee T, Nualkaew T, Buasuwan N, Hinna N, Paiboonsukwong K, Sripichai O, Svasti S, Winichagoon P, Fucharoen S, Jearawiriyapaisarn N. Development of DNA controls for detection of β-thalassemia mutations commonly found in Asian. Int J Lab Hematol. 2020 Dec;42(6):727-733. doi: 10.1111/ijlh.13292. Epub 2020 Jul 24.

5.Siriworadetkun S, Thubthed R, Thiengtavor C, Paiboonsukwong K, Khuhapinant A, Fucharoen S, Pattanapanyasat K, Vadolas J, Svasti S, Chaichompoo P. Elevated levels of circulating monocytic myeloid derived suppressor cells in splenectomised β-thalassaemia/HbE patients. Br J Haematol. 2020 Nov;191(3):e72-e76. doi: 10.1111/bjh.17012. Epub 2020 Aug 5.

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  • 1999-2011: Scholarship from the Medical Scholar Programs (Ph.D – M.D programs), Mahidol University, Thailand
  • 2001-2002: Scholarship for supported Ph.D. Thesis from The Ministry of University Affair and Faculty of Graduated Studies, Mahidol University, Thailand
  • 2001: Poster Presentation Award: Academic Forum II on Science and Technology Nov 29-30, 2001. Institute of Science and Technology for Research and Development, Mahidol University, Nakhon Pathom, Thailand.
  • 2003: Scholarship “Tomy Awards”: The 6th Conference of the Asia-Pacific International Molecular Biology Network (A-IMBN), Nov 11-13, 2003. National Museum of Emerging Science and Innovation, Tokyo, Japan.
  • 2003-2004: Thesis Publication/Presentation Awards for Graduate Students of Mahidol University for the Academic Year 2003-2004.
  • 2003-2004: Scholarship for Supported Presentation in an International Conference for Graduate Students of Mahidol University for the Academic Year 2003-2004.
  • 2006-2008: “FY2006 JSPS Postdoctoral Fellowship for Foreign Researchers”, Japan Society for the Promotion of Science (JSPS).
  • 2010: Exchange Medical Student in “IFMSA SCOPE” Program at Department of Nephrology, Rigshospitalet, Copenhagen University during 1-13 February 2010.
  • 2011: Clinical Elective in “Special Clinical Elective Programme” at Department of Opthalmology, Khoo Teck Puat Hospital, National University of Singapore during 1-12 August 2011.
  • 2013: Best Poster Presentation Award: National Thalassemia Conference 19th, 30 Oct-1Nov 2013. Khum Phucomm Hotel, Chiang Mai, Thailand.
  • 2014: Best Poster Presentation Award in Category “Prevention and Control”: National Thalassemia Conference 20th, 17-19 Dec 2014. Miracle Grand Convention, Bangkok, Thailand.
  • 2014: Best Poster Presentation Award in Category “Research and Laboratory Science”: National Thalassemia Conference 20th, 17-19 Dec 2014. Miracle Grand Convention, Bangkok, Thailand.
  • 2016: Representative of Thailand in “The 3rd Japan Medical Innovation Tour 2016” organized by Kyushu University and Japan Science and Technology Agency (JST), 14-21 Feb 2016.
  • 2016: Honorable mention Award for Oral Presentation: National Thalassemia Conference 21th, 9-11 Mar 2016. The Pullman Khon Kaen Raja Orchid Hotel, Khon Kaen, Thailand.
  • 2016: Best Oral Presentation Award: National Thalassemia Conference 21th, 9-11 Mar 2016. The Pullman Khon Kaen Raja Orchid Hotel, Khon Kaen, Thailand.
  • 2017: Best Oral Presentation Award: National Thalassemia Conference 22th, 6-7 Jul 2017. Miracle Convention Center, Bangkok, Thailand.
  • 2017: Best Poster Presentation Award (as Corresponding Author) : National Thalassemia Conference 22th, 6-7 Jul 2017. Miracle Convention Center, Bangkok, Thailand.
  • 2017: Certificate of Completion for two year fellowship with Asia Collaborative for medical Education (ACME) and NIH Fogarty International Research Ethics Education Program.