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Research Highlights


Neuroscience International Program
M.Sc. & Ph.D.

Academic Programs

1.Electrophysiology and Neuroimaging Techniques
  • EEG studies on cognitive interventions
    Measuring brain activity before and after cognitive interventions to assess brain plasticity and functional improvements.
  • Event-related potential (ERP) analyses in neurological diseases
    Using ERP techniques to detect early signs of nervous system disorders and monitor brain function changes.
  • Role of sleep and circadian rhythm in cognition
    Exploring how sleep patterns and biological clocks influence memory formation, attention, and learning abilities.
2.Child and Adolescent Brain Development
  • Sleep deprivation and executive function in children and adolescents
    Investigating how insufficient sleep impacts attention, memory, language processing, and decision-making skills in school-aged children and teenagers.
  • Development of metacognitive skills and academic success
    Investigating how children’s ability to think about their own thinking relates to their school performance over time.
  • Enhancing prosocial behavior through brain imaging and games
    Using collaborative tasks and neuroeconomic games to understand and promote prosocial decision-making in young people.
3.Neurodegeneration and Neuroprotection
  • Regulation of tryptophan metabolism in neuroinflammation
    Exploring how controlling tryptophan pathways can prevent cognitive impairments caused by methamphetamine-induced brain inflammation in animal models.
  • Mechanisms of pyroptotic cell death in cognitive impairment
    Studying how inflammation-driven cell death contributes to memory and cognitive decline after methamphetamine exposure.
  • Discovery of orexin receptor antagonists for insomnia treatment
    Investigating new compounds that block orexin receptors as a novel therapeutic strategy for sleep disorders.
  • Natural compound-based drug discovery for Alzheimer’s disease
    Identifying and testing small molecules derived from natural sources that could slow down or prevent Alzheimer’s disease progression.
4.Biomarkers and Pathogenesis of Brain Disorders
  • Biomarkers for brain and psychiatric disorders
    Searching for biological indicators that could lead to earlier diagnosis and better understanding of brain developmental and psychiatric conditions.
  • Astrocytic signaling in stroke injury
    Investigating how brain support cells (astrocytes) respond during ischemic events and contribute to brain damage and repair.
  • Cerebrovascular pathology in thalassemia
    Studying how vascular changes in genetic blood disorders like thalassemia can affect cognitive function using mouse models.
5.Stem Cell Research and Extracellular Vesicles
  • Engineered extracellular vesicles for heart regeneration
    Developing bioengineered vesicles from stem cells to promote heart cell survival and regeneration after injury.
  • Anti-aging effects of stem cell-derived exosomes
    Studying how exosomes from young stem cells can rejuvenate aging neurons and restore brain function.
  • Preconditioned microglia exosomes for neuroprotection
    Investigating how microglia, treated with anti-aging compounds, secrete protective vesicles that may enhance brain resilience.
6.Drug Discovery and Structure-Based Design
  • IDO-1 inhibitors for neuroinflammatory diseases
    Designing small molecules that inhibit the IDO-1 enzyme, a key player in brain inflammation and degeneration.
  • Computer-aided drug discovery for Alzheimer’s therapeutics
    Using advanced modeling and simulation tools to find new drug candidates that target mechanisms underlying Alzheimer’s disease.
  • Neurotoxicity of organophosphate pesticides
    Studying how common agricultural chemicals can cause long-term damage to the nervous system and increase the risk of brain diseases.
7.Biosensors and Nanotechnology for Neuroscience
  • Colorimetric biosensors for stress monitoring
    Developing simple color-change biosensors that detect stress-related biomarkers in biological samples.
  • Immunosensors for early Alzheimer’s disease detection
    Creating sensitive sensors that can identify Alzheimer’s disease biomarkers at early stages for potential diagnosis tools.
  • Nanomaterials for biological and medical applications
    Exploring the use of engineered nanoparticles to improve biosensor sensitivity and therapeutic delivery systems.
8. OMICs Technologies in Neuroscience
  • Transcriptomic and proteomic profiling of neuron development

    Analyzing gene and protein expression changes during the growth and differentiation of neuronal cells.

  • Stem cell secretome for rejuvenating aging cells

    Developing secreted factor cocktails from stem cells to promote repair and rejuvenation of aging tissues.

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