Sirirat Kumarn, Ph.D.
Assistant Professor
Organic chemistry approaches are used to develop efficient chemical processes to synthesise bioactive peptides to aid drug discovery and to turn agricultural waste into useful new composite materials.
Tel: 66 (0) 2441-9003 – 7 Ext. 1616
Email: sirirat.kum
mahidol.ac.th
Ph.D. (Chemistry), University of Cambridge, UK, 2008
Academic Program(s): Systems Biosciences
Despite the global disruption posed by COVID-19, the importance of chemical sciences – to bring about more efficient chemical processes and new compounds and materials – has not subsided, especially when the environment is still a big part of the picture. Our research interests involve the development of new chemical strategies to generate molecules and materials of interest through two main research programmes: (i) synthetic methodology to efficiently access bioactive peptidic compounds for application in drug discovery; and (ii) chemical processes to create alternative, biodegradable composite materials from agricultural waste, such as cassava bagasse, and from recycling important household waste of today, namely disposable masks and gloves.
1.Kumarn S, Churinthorn N, Nimpaiboon A, Sriring M, Ho C-C, Takahara A, et al. Investigating the Mechanistic and Structural Role of Lipid Hydrolysis in the Stabilization of Ammonia-Preserved Hevea Rubber Latex. Langmuir. 2018;34(43):12730-8.
2.Kumarn S, Chimnoi N, Ruchirawat S. Synthesis of integerrimide A by an on-resin tandem Fmoc-deprotection–macrocyclisation approach. Org Biomol Chem. 2013;11(44):7760-7.
3.Kumarn S, Oelke AJ, Shaw DM, Longbottom DA, Ley SV. A sequential enantioselective, organocatalytic route to chiral 1,2-oxazines and chiral pyridazines. Org Biomol Chem. 2007;5(16):2678-89.
4.Kumarn S, Shaw DM, Ley SV. A highly selective, organocatalytic route to chiral 1,2-oxazines from ketones. Chem Commun. 2006(30):3211-3.
5.Kumarn S, Shaw DM, Longbottom DA, Ley SV. A Highly Selective, Organocatalytic Route to Chiral Dihydro-1,2-oxazines. Org Lett. 2005;7(19):4189-91.
2015, Newton Fund Researcher Links Travel Grant 2015 (at the University of Cambridge, UK; Host: Prof. Steven V. Ley);
2011, Junior Research Fellowship 2011 by the French Embassy in Thailand (at the Institut de Chimie des Substances Naturelles (ICSN), CNRS, Gif-sur-Yvette, France; Host: Dr Géraldine Masson);
1996, The Outstanding Child of the Year by the National Council on Social Welfare of Thailand under the Royal Patronage of HM the King
